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Comments

You're looking at 1 of 1,070 antibodies for this target.

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(3976) TACE Antibody

A polyclonal rabbit antibody, supplied by Cell Signaling Technology, raised against Disintegrin and metalloproteinase domain-containing protein 17 (Human), cited in 36 publications, with 15 published images. Validated by knockdown. Applications used include WB, ICC-IF, IHC, IHC-IF, and 1 other.

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Supplier info
15 images
36 citations

General Information

Supplier
Cell Signaling Technology
Host
Rabbit
Type
Primary
Clonality
Polyclonal
Conjugate
Unconjugated
Target
Disintegrin and metalloproteinase domain-containing protein 17 (Human)
UniProt
P78536 - ADA17_HUMAN
Gene
ADAM17
Modification
Unmodified

Supplier provided information

Validations

None provided

Applications

  • Immunoprecipitation (IP)
  • Western Blotting (WB)

Reactivity

  • Chlorocebus sabaeus (Green monkey)
  • Homo sapiens (Human)

Additional product information

Synonyms

ADAM 17 ADAM17 CSVP Disintegrin and metalloproteinase domain-containing protein 17 Snake venom-like protease TACE TNF-alpha convertase TNF-alpha-converting enzyme ADAM metallopeptidase domain 17 ADAM metallopeptidase domain 18 ADAM18 CD156B MGC71942 TNF-alpha converting enzyme tumor necrosis factor, alpha, converting enzyme ADA17 TNF-alpha convertase enzyme NISBD a disintegrin and metalloproteinase 17 NISBD1 cartilage snake venom-like protease

Protein Names

Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, ADA17_HUMAN

UniProt Code History

P78536, O60226

Gene Synonyms

ADAM17, TACE, CSVP, NISBD, ADAM18, CD156B, NISBD1, HYPT16

Supplier also known as

CST, Cell Signalling, New England Biolabs


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15 images
36 citations

found in the literature

Reactivity
  • Homo sapiens (Human)
  • Mus musculus (House mouse)
  • Capra aegagrus hircus (Goat)
  • Lama glama (Llama)
  • 2 others
Applications
  • WB
  • ICC-IF
  • IHC
  • IHC-IF
  • 1 other
Dilutions
  • None Available

Loading published images for this product

Obesity-induced pyroptotic adipocyte death leads to TREM2-dependent macrophage dysfunction and adipose tissue inflammation.

View PDF

In IScience on 16 January 2026 by Choi, C., Lee, J., et al.

Elevated expression and secretion of TGF-α contribute to Temozolomide resistance in human glioblastoma cells.

View PDF

In Cancer Cell International on 28 November 2025 by Yang, J. T., Lee, I. N., et al.

Applications:

IHC and WB

Reactivity:

Homo sapiens (Human)

Characterization and comparative analysis of multifunctional natural killer cell engagers during antitumor responses.

View PDF

In Cell Reports Medicine on 20 May 2025 by Lin, H., Case, R., et al.

Applications:

WB

Insight into mammary gland development and tumor progression in an E2F5 conditional knockout mouse model.

View PDF

In Oncogene on 1 November 2024 by To, B., Broeker, C., et al.

Applications:

WB

Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection.

View PDF

In Frontiers in Immunology on 6 February 2024 by Anthofer, M., Windisch, M., et al.

Applications:

WB

ITGB1 and DDR activation as novel mediators in acquired resistance to osimertinib and MEK inhibitors in EGFR-mutant NSCLC.

View PDF

In Scientific Reports on 4 January 2024 by De Rosa, C., De Rosa, V., et al.

Applications:

WB

Reactivity:

Homo sapiens (Human)

Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding.

View Preprint View PDF

In Nature Communications on 14 December 2023 by Yamada, K., Shioya, R., et al.

Applications:

PLA

Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis.

View PDF

In Membranes on 5 August 2023 by Sperrhacke, M., Leitzke, S., et al.

Applications:

WB

Reactivity:

Homo sapiens (Human)

ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression.

View PDF

In International Journal of Molecular Sciences on 22 April 2023 by Yang, J. T., Lee, I. N., et al.

Applications:

WB

P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction.

View PDF

In Cell Communication and Signaling : CCS on 12 April 2023 by Chen, Q., Li, Y., et al.

Validations:

Knockdown

Applications:

IHC-IF and WB

Reactivity:

Mus musculus (House mouse)

Images:
Cell Signaling Technology logo
  • info@cellsignal.com
  • 877-678-8324
  • 3 Trask Lane, Danvers, MA 01923, USA.

Cell Signaling Technology

Related Searches

  • Target
    • P78536 antibodies
    • ADAM17 antibodies
    • TACE antibodies
    • CSVP antibodies
    • NISBD antibodies
    • ADAM18 antibodies
    • CD156B antibodies
    • NISBD1 antibodies
    • HYPT16 antibodies

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