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Comments

Compare products from hundreds of suppliers.

Add additional filters to your search, and evaluate citations, images and supplier data, to find the best reagent for your task.

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(12683) MDR1/ABCB1 (D3H1Q) Rabbit Monoclonal Antibody

A recombinant monoclonal rabbit antibody, supplied by Cell Signaling Technology, raised against ATP-dependent translocase ABCB1 (Human), cited in 55 publications, with 22 published images. Applications used include WB, FC/FACS, SW - Size, and WB post IP.

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Supplier info
22 images
55 citations

General Information

Supplier
Cell Signaling Technology
Host
Rabbit
Type
Primary
Clonality
Recombinant (D3H1Q)
Recombinant
Yes
Conjugate
Unconjugated
Target
ATP-dependent translocase ABCB1 (Human)
UniProt
P08183 - MDR1_HUMAN
Gene
ABCB1
Modification
Unmodified

Supplier provided information

Validations

None provided

Applications

  • Immunoprecipitation (IP)
  • Western Blotting (WB)

Reactivity

  • Homo sapiens (Human)

Additional product information

Synonyms

ABCB1 ATP-binding cassette sub-family B member 1 MDR1 Multidrug resistance protein 1 P-glycoprotein 1 PGY1 ABC20 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ATP-binding cassette, subfamily B, member 1 CD243 CLCS GP170 MGC163296 P-GP colchicin sensitivity doxorubicin resistance ATP binding cassette subfamily B member 1 ATP-dependent translocase ABCB1 Phospholipid transporter ABCB1

Protein Names

ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, Multidrug resistance protein 1, P-glycoprotein 1, Phospholipid transporter ABCB1, MDR1_HUMAN

UniProt Code History

P08183, A8K294, B5AK60, Q12755, Q14812

Gene Synonyms

ABCB1, MDR1, PGY1, CLCS, P-GP, ABC20, CD243, GP170, ENPAT, p-170

Supplier also known as

CST, Cell Signalling, New England Biolabs


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22 images
55 citations

found in the literature

Reactivity
  • Homo sapiens (Human)
  • Mus musculus (House mouse)
  • Cricetulus migratorius (Armenian hamster)
  • Equus caballus (Horse)
  • 1 other
Applications
  • WB
  • FC/FACS
  • SW - Size
  • WB post IP
Dilutions for
  • 1:1,000
  • 1:500

Loading published images for this product

MHY5535, a novel PPARα antagonist, sensitizes ovarian cancer stem cells to chemotherapy by disrupting fatty acid oxidation-dependent mitochondrial metabolism.

In Biomedicine Pharmacotherapy = Biomédecine Pharmacothérapie on 12 August 2026 by Shin, M. J., Noh, S. G., et al.

Applications:

WB

Reactivity:

Homo sapiens (Human)

Matrix Stiffness Directs Stemness Signatures in Breast Cancer.

In Advanced Healthcare Materials on 1 July 2026 by Kopecky, C., Pandzic, E., et al.

Vernodalin and Gymnanthemum extensum Crude Extracts Exhibit In Vitro Anticancer Activity with Differential Regulation of Cancer-Associated Signaling Proteins in Breast and Ovarian Cancer Cells.

View PDF

In Biomedicines on 11 June 2026 by Faisal, M., Sukpondma, Y., et al.

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity.

View PDF

In International Journal of Oncology on 1 April 2026 by Mukinovic, E., Federmann, S., et al.

Applications:

WB

Reactivity:

Mus musculus (House mouse)

Valproate reactivates HTLV-1 tax and reduces ABCB1/MDR1 expression in PBMCs derived from ATLL patients.

View PDF

In Frontiers in Oncology on 30 March 2026 by Mourouvin, C., Tram, J., et al.

Applications:

FC/FACS and WB

Reactivity:

Homo sapiens (Human)

Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor.

View PDF

In Cell Reports on 24 March 2026 by Fleming, A. M., Jablonowski, C. M., et al.

Applications:

WB

PHLDA1 silencing in IMR-32 human neuroblastoma cells results in ABCB1 overexpression, augments chemoresistance and leads to increased growth of tumors.

View PDF

In Scientific Reports on 22 December 2025 by Kudrycka, M., Horwacik, I., et al.

Applications:

WB

Mechanisms and Ways to Overcome Acquired Resistance of Cancer Cells to Mcl-1 Antagonists.

In Biochemistry. Biokhimii?a on 1 December 2025 by Pervushin, N. V., Valdez Fernandez, B. Y., et al.

Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer.

View PDF

In Cell Reports Medicine on 17 June 2025 by Tighe, A., Nelson, L., et al.

Reactivity:

Homo sapiens (Human)

High cholesterol increases myeloma tumour burden and promotes resistance to bortezomib

View PDF

Preprint on BioRxiv : the Preprint Server for Biology on 24 January 2025 by Gámez, B., Whipp, D., et al.

Applications:

WB

Reactivity:

Equus caballus (Horse)

Cell Signaling Technology logo
  • info@cellsignal.com
  • 877-678-8324
  • 3 Trask Lane, Danvers, MA 01923, USA.

Cell Signaling Technology

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