CiteAb - Data Accelerating Science Data Accelerating Science
Menu
  • Reagent Search
    • Antibodies
      Recombinant, monoclonal & polyclonal antibodies and primary & secondary antibodies.
    • Biochemicals
      Carbohydrates, peptides, bioactive small molecules, buffers, dyes and lipids.
    • Cell Lines & Models
      Cell lines, tissues, bacteria & viruses, and animal models.
    • Kits & Assays
      ELISAs, multiplex immunoassay kits, detection/staining kits and conjugation/labelling kits.
    • Instruments
      Microscopes, flow cytometers, spectrometers, and other laboratory instruments.
    • Nucleotides
      Plasmids, primers, RNA, siRNA, shRNA, gRNA, viral vectors and particles.
    • Proteins
      Enzymes, growth factors, binding proteins (e.g. streptavidin) and protein mixtures (e.g. bovine serum).
  • Image Search
  • Custom Suppliers
    • Antibody Suppliers
      Polyclonal, monoclonal, recombinant or alternative affinity reagent production.
    • Cell line Suppliers
      Knockout cell lines, knockin cell lines, gene activation & repression and reporter cell lines.
    • Histology Suppliers
      Immunohistochemistry (IHC), in situ hybridisation (ISH), tissue microarray staining (TMA), and more.
    • Peptides Suppliers
      Standard and modified sequences, fluorescent, isotope and radioactive labelled peptides, and more.
    • Sequencing Suppliers
      Whole Genome Sequencing, Antibody Sequencing, Targeted Sequencing, and more.
  • Supplier Partnerships
  • Data Services
    • Reagent Suppliers
      Powerful life science market data, accurate product citations & published images and listing on our popular reagent search engine.
    • Pharma, Biotech & Academic Research Institutions
      Accelerate preclinical research by licensing our comprehensive life science reagent database for totally flexible and private use.
    • Investment, Research & Advisory Companies
      Power unique and quantitative analysis into life science reagent and equipment manufacturer performance to help you make more informed investment decisions.
    • Scientific Publishers
      Partner with CiteAb to maximise exposure, researcher benefit and revenue from your publications.
  • Sign in or Register
Sign in or Register
Comments

You're looking at 1 of 511 antibodies for this target.

Compare products from hundreds of suppliers. Add additional filters to your search, and evaluate citations, images and supplier data, to find the best reagent for your task.

Search 511 antibodies

(12601-1-AP) GCLC Polyclonal antibody

A polyclonal rabbit antibody, supplied by Proteintech, raised against Glutamate--cysteine ligase catalytic subunit (Human), cited in 166 publications, with 39 published images. Validated by knockdown. Applications used include WB, IHC, IF, IHC-IF, and 2 others.

Go to:
Supplier info
39 images
166 citations

General Information

Supplier
Proteintech
Host
Rabbit
Type
Primary
Clonality
Polyclonal
Conjugate
Unconjugated
Target
Glutamate--cysteine ligase catalytic subunit (Human)
UniProt
P48506 - GSH1_HUMAN
Gene
GCLC
Modification
Unmodified

Supplier provided information

Validations

None provided

Applications

  • Enzyme-linked immunosorbent assay (ELISA)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)

Reactivity

  • Homo sapiens (Human)
  • Mus musculus (House mouse)
  • Rattus norvegicus (Rat)

Additional product information

Synonyms

Gamma ECS, GCLC, GCS, GCS heavy chain, GLCL, GLCLC

Protein Names

Glutamate--cysteine ligase catalytic subunit, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCS heavy chain, GSH1_HUMAN

UniProt Code History

P48506, Q14399

Gene Synonyms

GCLC, GLCL, GLCLC, GCL, GCS, CNSHA7


View additional product information

Comments

for this reagent

Add your comment here...
Enabling you to share comments privately within your lab, helping to avoid duplicated effort.
Get free early access and help us shape this new feature. Join the private beta

39 images
166 citations

found in the literature

Reactivity
  • Homo sapiens (Human)
  • Mus musculus (House mouse)
  • Rattus norvegicus (Rat)
  • Capra aegagrus hircus (Goat)
Applications
  • WB
  • IHC
  • IF
  • IHC-IF
  • 2 others
Dilutions for
  • 1:500
  • 1:1,000
Dilutions for
  • 1:200

Loading published images for this product

Nrf2 deficiency in myeloid cells accelerates atherosclerosis by promoting the inflammatory response and impairing efferocytosis.

In Journal of Advanced Research on 1 September 2026 by Xu, X., Liu, C., et al.

Applications:

WB

Reactivity:

Homo sapiens (Human)

The miR-339-5p/ACSL4 Pathway Drives Ferroptosis in Macrophages Exposed to Silica Nanoparticles.

View PDF

In Frontiers in Bioscience (Landmark Edition) on 24 July 2026 by Zhang, W., Li, Y., et al.

Applications:

WB

Proteomic Analysis Reveals AMPKα-Mediated Antiandrogen Resistance via Ferroptosis Suppression in Prostate Cancer.

In Cancer Science on 13 July 2026 by Shiota, M., Tanegashima, T., et al.

Applications:

WB

A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.

In Bioactive Materials on 1 July 2026 by Sun, X., Xie, S., et al.

Applications:

WB

TRIP13 protects LDHA from FBXW7-mediated degradation and drives glycolytic plasticity in colorectal cancer

View PDF

Preprint on Research Square on 17 June 2026 by Sheng, N., He, Q., et al.

Applications:

WB

Fructus lycii mitigates oxidative stress in dry age-related macular degeneration models via Nrf2/ARE pathway.

View PDF

In International Journal of Ophthalmology on 29 May 2026 by Peng, Y., Liang, L. Y., et al.

Applications:

WB

Reactivity:

Mus musculus (House mouse)

Melatonin suppresses ILC2-driven airway hyperreactivity via glutathione-dependent metabolic reprogramming.

View PDF

In Frontiers in Immunology on 27 May 2026 by Cain, J., Hurrell, B. P., et al.

Applications:

FC/FACS

Reactivity:

Mus musculus (House mouse)

Images:

CtBP promoted P4HB mediates SLC7A11 maturation to confer ferroptosis resistance in triple-negative breast cancer.

View PDF

In Journal of Experimental & Clinical Cancer Research : CR on 16 May 2026 by Wang, L., Xu, H., et al.

Applications:

WB

Glutamate-cysteine ligase catalytic related glutathione metabolism inhibited high mobility group box 1 release by regulating epithelium ferroptosis in asthma.

View PDF

In Journal of Thoracic Disease on 30 April 2026 by Liu, H., Zhong, C., et al.

Applications:

IHC and WB

Transcriptomics, Proteomics and Network Pharmacology Reveal the Mechanisms of Cantharidin-Induced Kidney Injury in Rats.

View PDF

In Current Issues in Molecular Biology on 29 April 2026 by Duan, X., Zhao, C., et al.

Applications:

WB

Reactivity:

Rattus norvegicus (Rat)

Images:
Proteintech logo
  • proteintech@ptglab.com
  • +1312-455-8498
  • United States

Proteintech

Related Searches

  • Target
    • P48506 antibodies
    • GCLC antibodies
    • GLCL antibodies
    • GLCLC antibodies
    • GCL antibodies
    • GCS antibodies
    • CNSHA7 antibodies

Custom Antibodies

If you can't find the antibody you're looking for, why not consider a custom reagent from one of these suppliers.

Custom antibody suppliers

Calculators

A collection of useful calculators with more to come!

Use dilution calculator

Report a Problem

Spotted a mistake? Please let us know so that we can put it right!

Report a problem
156 more citations
Register a CiteAb account today to view them.
Sign in or Register now

Join thousands of people who already enjoy the CiteAb newsletter

Stay up to date with improvements to the CiteAb Explore Platform and data services, news of our partnerships, product launches and the CiteAb Awards, and get our latest market data analysis straight to your inbox.

Sign up
×

We just need a few more details to better tailor our newsletter to you:

CiteAb Explore Platform
  • Image search engine
  • Antibody search engine
  • Biochemical search engine
  • Cell Lines & Models search engine
  • Kits & Assays search engine
  • Instruments search engine
  • Nucleotide search engine
  • Protein search engine
  • Custom suppliers
  • Request a Demo
Research Resources
  • Antibody dilution calculator
  • Molarity calculator
  • Finding the right antibody
  • Citing an antibody
Data Licensing
  • Pharma/Biotech
  • Finance
  • Publishers
  • Integrations
Market Data
  • Antibody market data
  • Biochemical market data
  • Cell Lines & Models market data
  • Instrument market data
  • Kits & Assay market data
  • Protein market data
Supplier Partnerships
  • Citation & Image Provision
  • Listing on CiteAb
  • Market Data
  • Case Studies
CiteAb Information
  • Our story
  • Blog
  • Contact
  • Careers
  • CiteAb publications
  • CiteAb awards
  • Facebook
  • LinkedIn
  • Instagram
The world's largest antibody search engine, with results ranked by citations.

Data Accelerating Science

CiteAb helps researchers find reliable reagents through the Explore Platform, combining powerful reagent and image search tools. We also license our world-class data to pharma & biotech companies, investors and sci-tech companies, and partner with leading life science suppliers.

Publication metadata is provided by PubMed®, a database of the US National Library of Medicine. PubMed® is a registered trademark of US National Library of Medicine.

Company registered in England #08530854. VAT #179706954.
Copyright © CiteAb Ltd 2026. All rights reserved.

  • Privacy policy
  • Cookie policy
  • Terms of use
  • Subscription Terms and Conditions

In partnership with:

  • Storm Consultancy
  • University of Bath
Proud recipient of the Queen's Award for Innovation 2022