(T126856) Thalidomide

An inhibitor, supplied by Aladdin Scientific Corporation, cited in 8 publications, with Pubchem CID 5426.

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General Information

Supplier

Aladdin Scientific Corporation

PubChem CID

Function

Inhibitor

ChEBI ID

CHEBI:74947

Molecular Weight

258.23 g/mol

InChIKey

UEJJHQNACJXSKW-UHFFFAOYSA-N

IUPAC Name

2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Common Name

Thalidomide

Synonyms

Sedalis , Sedisperil , Synovir , Talismol , Thalidomide Celgene , UNII-4Z8R6ORS6L , .alpha.-N-Phthalylglutaramide , Algosediv , Neaufatin , Pangul , Pro-ban M , thalidomide , 3-Phthalimidoglutarimide , Imida-lab , Psychotablets , Distaxal , Imidene , Dist

Supplier provided information

Applications

None provided

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8 citations

found in the literature

Applications

None Available

Dilutions

None Available

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The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.

In Frontiers in Medicine on 24 June 2022 by Rosa, T. L. S. A., Mendes, M. A., et al.

Anti-angiogenic drugs: direct anti-cancer agents with mitochondrial mechanisms of action.

In Oncotarget on 24 October 2017 by Quayle, L. A., Pereira, M. G., et al.

Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity.

In Nature Medicine on 1 July 2016 by Eichner, R., Heider, M., et al.

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide.

In Leukemia on 1 November 2012 by López-Girona, A., Mendy, D., et al.

Novel thalidomide analogues from diamines inhibit pro-inflammatory cytokine production and CD80 expression while enhancing IL-10.

In Biomedicine Pharmacotherapy = Biomédecine Pharmacothérapie on 1 July 2012 by Mazzoccoli, L., Cadoso, S. H., et al.

Identification of a primary target of thalidomide teratogenicity.

In Science on 12 March 2010 by Ito, T., Ando, H., et al.

Primary function analysis of human mental retardation related gene CRBN.

In Molecular Biology Reports on 1 June 2008 by Xin, W., Xiaohua, N., et al.

Identification and functional characterization of cereblon as a binding protein for large-conductance calcium-activated potassium channel in rat brain.

In Journal of Neurochemistry on 1 September 2005 by Jo, S., Lee, K. H., et al.