(A113142) Actinomycin D

A lipid which acts as an inhibitor, supplied by Aladdin Scientific Corporation, cited in 12 publications, with Pubchem CID 457193.

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General Information

Supplier

Aladdin Scientific Corporation

PubChem CID

Classification

Lipid

Function

Inhibitor

ChEBI ID

CHEBI:27666

Molecular Weight

1255.4 g/mol

InChIKey

RJURFGZVJUQBHK-IIXSONLDSA-N

IUPAC Name

2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide

Common Name

Dactinomycin

Synonyms

Dactinomicina , DTXSID9020031 , Glycopeptide, 4a , GNF-Pf-2290 , ACT D , ACTINOMYCIN D [JAN] , Actinomycin I , Q7277486 , ACT (antibiotic) , AD (VAN) , Dactinomicina (INN-Spanish) , Dactinomycinum (INN-Latin) , GTPL5664 , 2-amino-4,6-dimethyl-3-oxo-1-N,9-

Supplier provided information

Applications

None provided

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12 citations

found in the literature

Applications

None Available

Dilutions

None Available

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Melatonin antagonizes ovarian aging via YTHDF2-MAPK-NF-κB pathway.

In Genes Diseases on 1 March 2022 by Zhu, R., Ji, X., et al.

c-Myc-activated USP2-AS1 suppresses senescence and promotes tumor progression via stabilization of E2F1 mRNA.

In Cell Death & Disease on 27 October 2021 by Li, B., Zhang, G., et al.

ZEB1-induced LINC01559 expedites cell proliferation, migration and EMT process in gastric cancer through recruiting IGF2BP2 to stabilize ZEB1 expression.

In Cell Death & Disease on 6 April 2021 by Shen, H., Zhu, H., et al.

The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation.

In Molecular Cancer on 23 November 2020 by Chen, L. Y., Wang, L., et al.

Nucleolar stress regulates stromal-epithelial transition via NPM1 during decidualization.

In Reproduction (Cambridge, England) on 1 October 2020 by Liang, Y. X., Hu, W., et al.

Long noncoding RNA EMS connects c-Myc to cell cycle control and tumorigenesis.

In Proceedings of the National Academy of Sciences of the United States of America on 16 July 2019 by Wang, C., Yang, Y., et al.

Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer.

In Cell Death & Disease on 16 May 2019 by Zhu, L., Zhu, Y., et al.

Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression.

In Molecular Cancer on 30 March 2019 by Huang, X., Li, Z., et al.

CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.

In Immunity on 19 March 2019 by Liu, J., Zhang, X., et al.

CIRBP is a novel oncogene in human bladder cancer inducing expression of HIF-1α.

In Cell Death & Disease on 12 October 2018 by Lu, M., Ge, Q., et al.