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(1292) Rapamycin

A bioactive compound which acts as an inhibitor, supplied by Tocris Bioscience, cited in 224 publications, with Pubchem CID 5284616. Applications used include WB, FC/FACS, ICC-IF, Cell Culture, and 3 others.

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Supplier info
57 images
224 citations

General Information

Supplier
Tocris Bioscience
PubChem CID
5284616
Classification
Bioactive compound
Function
Inhibitor
ChEBI ID
CHEBI:9168
Lipid Maps® ID
LMPK06000003
Molecular Weight
914.2 g/mol
InChIKey
QFJCIRLUMZQUOT-HPLJOQBZSA-N
IUPAC Name
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Common Name
Sirolimus
Synonyms
Antibiotic AY 22989, NSC 226080, AY 22989, SILA 9268A, Sirolimus

Supplier provided information

Applications

None provided


Additional product information

Supplier also known as

Bio-Techne, Cookson


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57 images
224 citations

found in the literature

Applications
  • WB
  • FC/FACS
  • ICC-IF
  • Cell Culture
  • 3 others
Dilutions
  • None Available

Loading published images for this product

A Rosella-PLIN2 knock-in mouse reveals lipophagy and immunometabolic interplay in atherosclerosis.

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In Autophagy on 1 September 2026 by Laval, T., Joyce, N., et al.

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1.

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In FEBS Open Bio on 1 May 2026 by Lehmkuhl, I., Amin, K., et al.

HIV gp120 induces TREM1 expression through TLR-PGE₂ signalling in human monocyte-derived microglia.

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In Journal of Neuroinflammation on 5 March 2026 by Mahama, A., Rawat, P., et al.

PTEN-mTORC2 signaling module controls antibody isotype selection and antiviral humoral immunity.

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In Frontiers in Immunology on 26 February 2026 by Thapa, B., Lee, Y., et al.

Maternal milk-derived lipids dictate neonatal macrophage phenotype and function.

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In IScience on 19 December 2025 by Liu, L., Yang, J., et al.

The MARK2 kinase acts as a gatekeeper of CD28-dependent co-stimulation in T cells

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Preprint on BioRxiv : the Preprint Server for Biology on 14 October 2025 by Ferran, H., Marconi, F., et al.

Applications:

FC/FACS and WB

Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry.

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In Nature on 1 October 2025 by Paul, D., Bolhuis, D. L., et al.

Applications:

FC/FACS and WB

Images:

Ligand-specific regulation of a binary enhancer code dictating cellular senescence.

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In Proceedings of the National Academy of Sciences of the United States of America on 17 June 2025 by Suter, T., Friedman, M. J., et al.

Applications:

IHC

Investigating the use of cuprizone and lysolecithin to model demyelination ex vivo in sagittal rat brain organotypic slice cultures.

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In Frontiers in Cellular Neuroscience on 6 June 2025 by Hawker, B., Connor, B., et al.

Applications:

IHC-IF

Images:

Kaposi sarcoma-associated herpesvirus cooperates with Epstein-Barr virus to co-transform a small set of human B cells oncogenically.

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In PLoS Pathogens on 1 June 2025 by Hayes, M., Wang, W., et al.

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  • 1-800-343-7475
  • Minneapolis, USA

Tocris Bioscience

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