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Comments

(3241) Ko 143

An inhibitor, supplied by Tocris Bioscience, cited in 22 publications, with Pubchem CID 10322450. Applications used include FC/FACS.

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Supplier info
22 citations

General Information

Supplier
Tocris Bioscience
PubChem CID
10322450
Function
Inhibitor
ChEBI ID
CHEBI:95026
Molecular Weight
469.6 g/mol
InChIKey
NXNRAECHCJZNRF-JBACZVJFSA-N
IUPAC Name
tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate
Common Name
Ko 143

Supplier provided information

Applications

None provided


Additional product information

Supplier also known as

Bio-Techne, Cookson


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0 images
22 citations

found in the literature

Applications
  • FC/FACS
Dilutions
  • None Available

Published images

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Pharmacological Inhibition of SP1 Reverses Cancer Stemness and Enhances Sorafenib Efficacy in Hepatocellular Carcinoma.

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In Cells on 22 May 2026 by Padelli, M., Desterke, C., et al.

Applications:

FC/FACS

MDR1-EXPRESSING CD4+ T CELLS WITH TH1.17 FEATURES RESIST TO NEOADJUVANT CHEMOTHERAPY AND ARE ASSOCIATED WITH BREAST CANCER CLINICAL RESPONSE.

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In Journal for Immunotherapy of Cancer on 1 November 2023 by Di Roio, A., Hubert, M., et al.

Applications:

FC/FACS

Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop.

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In Membranes on 4 October 2023 by Mózner, O., Zámbó, B., et al.

Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes.

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In ACS Chemical Biology on 21 October 2022 by Barghout, S. H., Mann, M. K., et al.

ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation.

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In Redox Biology on 1 May 2021 by Zhang, T., Tsutsuki, H., et al.

A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity.

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In JCI Insight on 8 March 2021 by Barghout, S. H., Aman, A., et al.

Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters.

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In Pharmaceutics on 9 January 2021 by Telbisz, Á., Ambrus, C., et al.

Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain Barrier.

In Stem Cells on 1 December 2018 by Delsing, L., Dönnes, P., et al.

IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process.

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In Oncotarget on 13 December 2016 by Le Coz, V., Zhu, C., et al.

In Vivo Bioluminescent Imaging of ATP-Binding Cassette Transporter-Mediated Efflux at the Blood-Brain Barrier.

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In Methods in Molecular Biology (Clifton, N.J.) on 19 July 2016 by Bakhsheshian, J., Wei, B. R., et al.

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