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Comments

(4745) LIMKi 3

An inhibitor, supplied by Tocris Bioscience, cited in 10 publications, with Pubchem CID 56965901. Applications used include WB, IHC, and IHC-IF.

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Supplier info
10 images
10 citations

General Information

Supplier
Tocris Bioscience
PubChem CID
56965901
Function
Inhibitor
ChEBI ID
CHEBI:138670
Molecular Weight
431.3 g/mol
InChIKey
IVUGBSGLHRJSSP-UHFFFAOYSA-N
IUPAC Name
N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)pyrazol-5-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
Common Name
LIMKi3
Synonyms
BMS 5

Supplier provided information

Applications

None provided


Additional product information

Supplier also known as

Bio-Techne, Cookson


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10 images
10 citations

found in the literature

Applications
  • WB
  • IHC
  • IHC-IF
Dilutions
  • None Available

Loading published images for this product

Structural and functional alterations of neurons derived from sporadic Alzheimer's disease hiPSCs are associated with downregulation of the LIMK1-cofilin axis.

View PDF

In Alzheimer's Research & Therapy on 19 December 2024 by Sollazzo, R., Li Puma, D. D., et al.

Applications:

IHC-IF and WB

Semaphorin-3A regulates liver sinusoidal endothelial cell porosity and promotes hepatic steatosis.

View PDF

In Nat Cardiovasc Res on 1 June 2024 by Eberhard, D., Balkenhol, S., et al.

Applications:

IHC and WB

Images:

Arhgef6 (alpha-PIX) cytoskeletal regulator signals to GTPases and Cofilin to couple T cell migration speed and persistence.

In Journal of Leukocyte Biology on 1 November 2021 by Mamula, D., Korthals, M., et al.

The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse.

View PDF

In Frontiers in Cell and Developmental Biology on 1 May 2021 by Bolger-Munro, M., Choi, K., et al.

Applications:

WB

Images:

Cyclosporine A inhibits MRTF-SRF signaling through Na+/K+ ATPase inhibition and actin remodeling.

View PDF

In FASEB BioAdvances on 1 September 2019 by Burat, B., Faucher, Q., et al.

Endothelin type B receptor promotes cofilin rod formation and dendritic loss in neurons by inducing oxidative stress and cofilin activation.

View PDF

In The Journal of Biological Chemistry on 16 August 2019 by Tam, S. W., Feng, R., et al.

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.

View PDF

In Cell on 7 February 2019 by Georgouli, M., Herraiz, C., et al.

The actin filament bundling protein α-actinin-4 actually suppresses actin stress fibers by permitting actin turnover.

View PDF

In The Journal of Biological Chemistry on 14 September 2018 by Kemp, J. P. & Brieher, W. M.

Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice.

View PDF

In Journal of Cerebral Blood Flow & Metabolism on 1 January 2018 by Manaenko, A., Yang, P., et al.

Cytoskeletal adaptivity regulates T cell receptor signaling.

View PDF

In Science Signaling on 7 March 2017 by Thauland, T. J., Hu, K. H., et al.

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  • 1-800-343-7475
  • Minneapolis, USA

Tocris Bioscience

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