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Comments

(5449) Erastin

An activator, supplied by Tocris Bioscience, cited in 31 publications, with Pubchem CID 11214940. Applications used include FC/FACS, IHC, WB, and ICC-IF.

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Supplier info
65 images
31 citations

General Information

Supplier
Tocris Bioscience
PubChem CID
11214940
Function
Activator
ChEBI ID
CHEBI:94287
Molecular Weight
547.0 g/mol
InChIKey
BKQFRNYHFIQEKN-UHFFFAOYSA-N
IUPAC Name
2-[1-[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one
Common Name
Erastin

Supplier provided information

Applications

None provided


Additional product information

Supplier also known as

Bio-Techne, Cookson


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65 images
31 citations

found in the literature

Applications
  • FC/FACS
  • IHC
  • WB
  • ICC-IF
Dilutions
  • None Available

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Microfluidic compartmentalization reveals that ferrostatin-1 restores directional mitochondrial transport in Aβ-challenged neurons.

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In Lab On A Chip on 14 July 2026 by Majerníková, N., Corci, B., et al.

MESH1-mediated coenzyme A degradation drives ferroptosis sensitivity and muscle pathology.

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In The Journal of Clinical Investigation on 1 June 2026 by Lin, C. C., Rose, J., et al.

Exposure to diesel exhaust particles accelerated neuronal cell death in xenoferroptosis-susceptible cells.

In Journal of Environmental Sciences (China) on 1 May 2026 by Yan, H., Zhang, L., et al.

Applications:

IHC

Ferroptosis as a novel alternative cell death model in Hashimoto´s thyroiditis.

In Biomedicine Pharmacotherapy = Biomédecine Pharmacothérapie on 1 May 2026 by Sacristán-Gómez, P., Delgado-Martín, S., et al.

Applications:

FC/FACS

Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase.

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In The Journal of Clinical Investigation on 1 October 2025 by Lin, C. C., Lin, Y. T., et al.

Resveratrol Inhibits VDAC1-Mediated Mitochondrial Dysfunction to Mitigate Pathological Progression in Parkinson's Disease Model.

In Molecular Neurobiology on 1 June 2025 by Feng, S., Gui, J., et al.

EGR1 regulates oxidative stress and aldosterone production in adrenal cells and aldosterone-producing adenomas.

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In Redox Biology on 1 March 2025 by Pang, Y., Gong, S., et al.

Images:

NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation.

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In Cell Death & Disease on 18 October 2024 by Chen, S. Y., Wu, J., et al.

Applications:

FC/FACS

Images:

Protein CoAlation on TXNRD2 regulates mitochondrial thioredoxin system to protect against ferroptosis

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Preprint on BioRxiv : the Preprint Server for Biology on 18 May 2024 by Lin, C., Lin, Y., et al.

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response.

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In The EMBO Journal on 1 March 2024 by Vringer, E., Heilig, R., et al.

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  • 1-800-343-7475
  • Minneapolis, USA

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