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Comments

(S3604) Triptolide (PG490)

supplied by Selleck Chemicals, cited in 42 publications, with Pubchem CID 129010078. Applications used include FC/FACS, WB, ELISA, ICC-IF, and 2 others.

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Supplier info
11 images
42 citations

General Information

Supplier
Selleck Chemicals
PubChem CID
129010078
Molecular Weight
360.4 g/mol
InChIKey
DFBIRQPKNDILPW-LKUXBXJISA-N
IUPAC Name
(1S,2S,4S,5R,7S,8R,9S,11R,13R)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
Common Name
Triptolide (PG490)
Synonyms
NSC 163062

Supplier provided information

Applications

None provided


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11 images
42 citations

found in the literature

Applications
  • FC/FACS
  • WB
  • ELISA
  • ICC-IF
  • 2 others
Dilutions
  • None Available

Loading published images for this product

A two-pronged strategy eliminates dissociation artifacts for high-fidelity neuroimmune single-cell transcriptomics.

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In Communications Biology on 6 July 2026 by Yan, Y., Tang, B., et al.

KAS-CUT&Tag for direct mapping of transcription bubbles

Preprint on BioRxiv : the Preprint Server for Biology on 19 May 2026 by Wu, W., Greene, J. E., et al.

Parkinson's disease-associated PLA2G6 protects IP3R1 protein to control ER-mitochondria tethering and Ca2+ transfer.

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In Nature Communications on 19 March 2026 by Lin, Z. H., Xue, N. J., et al.

LLDT-8 attenuates brain metastasis in non-small cell lung cancer via selective p53 activation.

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In RSC Medicinal Chemistry on 16 December 2025 by Liu, J., Liang, L., et al.

Applications:

IHC, IHC-IF, and WB

KCTD10 is a sensor for co-directional transcription-replication conflicts.

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In Nature on 1 December 2025 by Kloeber, J. A., Chen, B., et al.

Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.

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In Chinese Medicine on 6 August 2025 by Ding, L., Chen, W., et al.

Applications:

ELISA and WB

Images:

Chromatin-bound U2AF2 splicing factor ensures exon inclusion.

In Molecular Cell on 15 May 2025 by Wu, W., Ahmad, K., et al.

Applications:

FC/FACS

Images:

HIRA protects telomeres against R-loop-induced instability in ALT cancer cells.

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In Cell Reports on 26 November 2024 by Lynskey, M. L., Brown, E. E., et al.

The BAF chromatin remodeler synergizes with RNA polymerase II and transcription factors to evict nucleosomes.

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In Nature Genetics on 1 January 2024 by Brahma, S. & Henikoff, S.

Applications:

FC/FACS

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.

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In Nature Genetics on 1 October 2023 by McCann, J. L., Cristini, A., et al.

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