(Asc-003) D-AP5

An amino acid which acts as an inhibitor, supplied by Ascent Scientific, cited in 20 publications, with Pubchem CID 135342.

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20 citations

General Information

Supplier

Ascent Scientific

PubChem CID

135342

Classification

Amino acid

Function

Inhibitor

Molecular Weight

197.13 g/mol

InChIKey

VOROEQBFPPIACJ-SCSAIBSYSA-N

IUPAC Name

(2R)-2-amino-5-phosphonopentanoic acid

Common Name

(R)-2-Amino-5-phosphonopentanoic acid

Synonyms

Abcam:ab120003

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Applications

None provided

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20 citations

found in the literature

Applications

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Dilutions

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Tonically active NMDA receptors--a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum.

In European Journal of Neuroscience on 1 January 2016 by Riebe, I., Seth, H., et al.

Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome.

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In The Journal of Neuroscience on 4 March 2015 by Tang, A. H. & Alger, B. E.

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus.

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In Neurobiology of Disease on 1 October 2014 by Rojas, A., Gueorguieva, P., et al.

Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation.

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In Nature Neuroscience on 1 March 2014 by Fan, X., Jin, W. Y., et al.

A local glutamate-glutamine cycle sustains synaptic excitatory transmitter release.

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In Neuron on 19 February 2014 by Tani, H., Dulla, C. G., et al.

Regulation of action potential delays via voltage-gated potassium Kv1.1 channels in dentate granule cells during hippocampal epilepsy.

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In Frontiers in Cellular Neuroscience on 25 December 2013 by Kirchheim, F., Tinnes, S., et al.

Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response.

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In The Journal of Neuroscience on 11 December 2013 by Gunn, B. G., Cunningham, L., et al.

Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP.

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In The Journal of Neuroscience on 5 June 2013 by Kaeser-Woo, Y. J., Younts, T. J., et al.

Kainate receptor post-translational modifications differentially regulate association with 4.1N to control activity-dependent receptor endocytosis.

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In The Journal of Biological Chemistry on 29 March 2013 by Copits, B. A. & Swanson, G. T.

Evaluation of glutamate concentration transient in the synaptic cleft of the rat calyx of Held.

In The Journal of Physiology on 1 January 2013 by Budisantoso, T., Harada, H., et al.

(Asc-003) D-AP5

General Information

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20 citations

found in the literature

Applications

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Published images

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(Asc-003) D-AP5

General Information

Supplier provided information

Applications

Additional product information

Comments for this reagent

0 images 20 citations found in the literature

Applications

Dilutions

Published images

Is this your product?

Calculators

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Comments

for this reagent

0 images

20 citations

found in the literature