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Comments

(5343) TPPB

A bioactive compound which acts as an activator, supplied by Tocris Bioscience, cited in 25 publications, with Pubchem CID 9935767. Applications used include FC/FACS, ICC-IF, and WB.

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Supplier info
15 images
25 citations

General Information

Supplier
Tocris Bioscience
PubChem CID
9935767
Classification
Bioactive compound
Function
Activator
Molecular Weight
501.5 g/mol
InChIKey
WOLVEMPZUIFSII-IHHOKICGSA-N
IUPAC Name
(2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide
Common Name
alpha-APP Modulator

Supplier provided information

Applications

None provided


Additional product information

Supplier also known as

Bio-Techne, Cookson


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15 images
25 citations

found in the literature

Applications
  • FC/FACS
  • ICC-IF
  • WB
Dilutions
  • None Available

Loading published images for this product

Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation.

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In Nature Communications on 2 April 2026 by Hogrebe, N. J., Schmidt, M. D., et al.

Human pancreatic organoids derived from pluripotent stem cells recapitulate pancreatic organogenesis

Preprint on BioRxiv : the Preprint Server for Biology on 31 October 2025 by Brassard, J. A., Tornabene, P., et al.

Complete loss of PAX4 causes transient neonatal diabetes in humans.

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In Molecular Metabolism on 1 September 2025 by Russ-Silsby, J., Lee, Y., et al.

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals.

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In Cell Reports on 26 August 2025 by D'Oliveira Albanus, R., Zhang, X., et al.

Controlling Human Stem Cell-Derived Islet Composition Using Magnetic Sorting.

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In Biotechnology and Bioengineering on 1 August 2025 by Kelley, A. B., Shunkarova, M., et al.

Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived islets.

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In Nature Communications on 7 February 2025 by Kim, M., Cho, S., et al.

Exploring optimal protocols for generating and preserving glucose-responsive insulin-secreting progenitor cells derived from human pluripotent stem cells.

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In European Journal of Cell Biology on 1 December 2024 by Tornabene, P. & Wells, J. M.

Multiplex Genome Editing of Human Pluripotent Stem Cells Using Cpf1.

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In Bio-protocol on 20 November 2024 by Ma, H.

Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection.

View Preprint View PDF

In Cell Stem Cell on 7 November 2024 by Yang, L., Han, Y., et al.

Tankyrase inhibition promotes endocrine commitment of hPSC-derived pancreatic progenitors.

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In Nature Communications on 9 October 2024 by Poon, F., Sambathkumar, R., et al.

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  • techsupport@bio-techne.com
  • 1-800-343-7475
  • Minneapolis, USA

Tocris Bioscience

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