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Comments

(HY-N0124) Dioscin

A lipid, supplied by MedChemExpress, cited in 10 publications, with Pubchem CID 119245. Applications used include FC/FACS, IHC, and WB.

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Supplier info
16 images
10 citations

General Information

Supplier
MedChemExpress
PubChem CID
119245
Classification
Lipid
ChEBI ID
CHEBI:74023
Lipid Maps® ID
LMST01080053
Molecular Weight
869.0 g/mol
InChIKey
VNONINPVFQTJOC-ZGXDEBHDSA-N
IUPAC Name
(2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
Common Name
(+)-Dioscin
Synonyms
Collettiside III; CCRIS 4123

Supplier provided information

Applications

None provided


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16 images
10 citations

found in the literature

Applications
  • FC/FACS
  • IHC
  • WB
Dilutions
  • None Available

Loading published images for this product

HIF-1α in CD4+ T cells drives gout pathogenesis via metabolic reprogramming and Th17 differentiation.

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In Journal of Pharmaceutical Analysis on 1 June 2026 by Song, S., Li, J., et al.

Targeting the BMI1-Noxa axis by Dioscin induces apoptosis in oral squamous cell carcinoma cells.

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In Journal of Cancer on 2 January 2025 by Fang, J., Wang, R., et al.

Applications:

FC/FACS, IHC, and WB

Dioscin inhibiting EGFR-mediated Survivin expression promotes apoptosis in oral squamous cell carcinoma cells.

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In Journal of Cancer on 27 July 2023 by Li, M., Zhao, Q., et al.

Applications:

FC/FACS, IHC, and WB

Images:

Cerebroprotection by dioscin after experimental subarachnoid haemorrhage via inhibiting NLRP3 inflammasome through SIRT1-dependent pathway.

In British Journal of Pharmacology on 1 September 2021 by Zhang, X. S., Lu, Y., et al.

Dioscin Promotes Prostate Cancer Cell Apoptosis and Inhibits Cell Invasion by Increasing SHP1 Phosphorylation and Suppressing the Subsequent MAPK Signaling Pathway.

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In Frontiers in Pharmacology on 15 August 2020 by He, S., Yang, J., et al.

Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.

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In Chemical Pharmaceutical Bulletin on 4 August 2020 by Zhang, Z., Han, K., et al.

Dioscin enhances osteoblastic cell differentiation and proliferation by inhibiting cell autophagy via the ASPP2/NF-κβ pathway.

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In Molecular Medicine Reports on 1 October 2017 by Zhu, C., Bao, N., et al.

Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family.

In Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban on 1 February 2014 by Chen, J., Li, H. M., et al.

Dioscin inhibits osteoclast differentiation and bone resorption though down-regulating the Akt signaling cascades.

In Biochemical and Biophysical Research Communications on 10 January 2014 by Qu, X., Zhai, Z., et al.

Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cells.

In Drug Research on 1 January 2014 by Qin, J., Kang, Y., et al.

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