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Comments

(2037-C5) Recombinant Human Complement Component C5a Protein

Supplied by R&D Systems, cited in 39 publications. Applications used include Functional, Cell Culture, Binding, and SPR.

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Supplier info
39 citations

General Information

Supplier
R&D Systems
Expression System
Escherichia coli
Bioactive
Yes
Nature
Recombinant
Protein Name
Complement C5
UniProt ID
P01031 - CO5_HUMAN
Species
Homo sapiens (Human)
Gene
C5

Supplier provided information

Applications

None provided

Reactivity

None provided


Additional product information

Synonyms

C5, C5A, Complement Component C5a, HE

Protein Names

Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CO5_HUMAN

UniProt Code History

P01031, Q14CJ0, Q27I61

Gene

C5, CPAMD4, C5a, C5D, C5b, ECLZB


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0 images
39 citations

found in the literature

Applications
  • Functional
  • Cell Culture
  • Binding
  • SPR
Reactivity
  • Homo sapiens (Human)
  • Mus musculus (House mouse)
Dilutions
  • None Available

Published images

We have not yet identified suitable images that show this product being used, more are being added all the time.

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C5a-Induced Autophagy Dysfunction Promotes Choroidal Neovascularization Through the ROS-Inflammatory Pathway.

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In Investigative Ophthalmology & Visual Science on 1 July 2025 by Du, Y., Feng, L., et al.

Applications:

Functional

Reactivity:

Homo sapiens (Human)

C5aR1 Promotes Invasion, Metastasis, and Poor Prognosis in Cutaneous Squamous Cell Carcinoma.

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In The American Journal of Pathology on 1 June 2025 by Heiskanen, L., Nissinen, L., et al.

Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.

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In Frontiers in Immunology on 13 May 2025 by Lika, J., Votava, J. A., et al.

Complement C5a promotes human retinal pigment epithelial cell viability and migration through SLC38A1-mediated glutamine metabolism.

In Medical Microbiology and Immunology on 13 May 2025 by Sun, Y., Hu, Y., et al.

Impact of Static Myoblast Loading on Protein Secretion Linked to Tenocyte Migration.

In Journal of Proteome Research on 2 May 2025 by Li, J., Zhou, X., et al.

Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis.

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In EMBO Molecular Medicine on 1 May 2025 by Margraf, A., Chen, J., et al.

Applications:

Functional

Reactivity:

Homo sapiens (Human)

The C5a/C5aR1 Axis Promotes Migration of Tolerogenic Dendritic Cells to Lymph Nodes, Impairing the Anticancer Immune Response.

In Cancer Immunology Research on 4 March 2025 by Senent, Y., Remírez, A., et al.

Applications:

Functional

Reactivity:

Homo sapiens (Human)

Inhibiting CFTR through inh-172 in primary neutrophils reveals CFTR-specific functional defects.

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In Scientific Reports on 28 December 2024 by Da Silva Cunha, A. L., Blanter, M., et al.

Applications:

Functional

Reactivity:

Homo sapiens (Human)

Activation induces shift in nutrient utilization that differentially impacts cell functions in human neutrophils.

View Preprint View PDF

In Proceedings of the National Academy of Sciences of the United States of America on 24 September 2024 by Britt, E. C., Qing, X., et al.

Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy.

In Journal of Structural Biology on 1 September 2024 by Yang, T., Li, J., et al.

Applications:

Functional

Reactivity:

Homo sapiens (Human)

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