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Comments

(2150-C5) Recombinant Mouse Complement Component C5a Protein

Supplied by R&D Systems, cited in 48 publications. Applications used include Functional, In Vivo, Cell Culture, ELISA, and 3 others.

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Supplier info
48 citations

General Information

Supplier
R&D Systems
Expression System
Escherichia coli
Bioactive
Yes
Nature
Recombinant
Protein Name
Complement C5
UniProt ID
P06684 - CO5_MOUSE
Species
Mus musculus (Mouse)
Gene
Hc

Supplier provided information

Applications

None provided

Reactivity

None provided


Additional product information

Synonyms

C5, C5A, Complement Component C5a, HE

Protein Names

Complement C5, Hemolytic complement, CO5_MOUSE

UniProt Code History

P06684, A2AS36

Gene

Hc, C5, He, C5a, Hfib2


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0 images
48 citations

found in the literature

Applications
  • Functional
  • In Vivo
  • Cell Culture
  • ELISA
  • 3 others
Reactivity
  • Mus musculus (House mouse)
  • Homo sapiens (Human)
Dilutions
  • None Available

Published images

We have not yet identified suitable images that show this product being used, more are being added all the time.

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Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma.

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In Allergy on 1 May 2026 by Dong, C., Lu, S., et al.

C5a-Induced Autophagy Dysfunction Promotes Choroidal Neovascularization Through the ROS-Inflammatory Pathway.

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In Investigative Ophthalmology & Visual Science on 1 July 2025 by Du, Y., Feng, L., et al.

Applications:

Functional

Reactivity:

Mus musculus (House mouse)

The C5a/C5aR1 Axis Promotes Migration of Tolerogenic Dendritic Cells to Lymph Nodes, Impairing the Anticancer Immune Response.

In Cancer Immunology Research on 4 March 2025 by Senent, Y., Remírez, A., et al.

Applications:

Functional

Reactivity:

Mus musculus (House mouse)

Lysosomes cell autonomously regulate myeloid cell states and immune responses

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Preprint on BioRxiv : the Preprint Server for Biology on 13 November 2024 by Tejwani, L., Balak, C., et al.

Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry.

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In Cell Reports on 28 November 2023 by Yang, F., Suo, M., et al.

Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network.

View Preprint View PDF

In Frontiers in Physiology on 26 June 2023 by Lilley, R. J., Taylor, K. D., et al.

Applications:

Functional

Reactivity:

Mus musculus (House mouse)

Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation.

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In Cancer Cell on 10 April 2023 by Mousset, A., Lecorgne, E., et al.

Investigation into the anti-airway inflammatory role of the PI3Kγ inhibitor JN-PK1: An in vitro and in vivo study.

In International Immunopharmacology on 1 October 2022 by Xiong, W., Jia, L., et al.

Applications:

Cell Culture

Reactivity:

Mus musculus (House mouse)

Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells.

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In Journal of Neuroinflammation on 14 July 2022 by Llorián-Salvador, M., Byrne, E. M., et al.

Applications:

Functional

Reactivity:

Mus musculus (House mouse)

Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.

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In Cell Death & Disease on 25 May 2022 by Brandolini, L., d'Angelo, M., et al.

Applications:

Functional

Reactivity:

Mus musculus (House mouse)

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