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Comments

(T9701) TRAIL human

A cytokine, supplied by SIGMA, cited in 11 publications.

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Supplier info
11 citations

General Information

Supplier
SIGMA
Purified
Yes (>= 98%)
Bioactive
No
Classification
Cytokine
Protein Name
Tumor necrosis factor ligand superfamily member 10
UniProt ID
P50591 - TNF10_HUMAN
Species
Homo sapiens (Human)
Gene
TNFSF10

Supplier provided information

Applications

  • Cell Culture
  • Immunofluorescence (IF)

Reactivity

None provided


Additional product information

Protein Names

Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, TNF-related apoptosis-inducing ligand, TNF10_HUMAN

UniProt Code History

P50591, A1Y9B3

Gene

TNFSF10, TRAIL, TL2, APO2L, CD253, Apo-2L, TNLG6A, TANCR

Supplier also known as

Millipore, Sigma Aldrich, Merck, Roche, Novagen, EMD


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0 images
11 citations

found in the literature

Applications
  • None Available
Reactivity
  • None Available
Dilutions
  • None Available

Published images

We have not yet identified suitable images that show this product being used, more are being added all the time.

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Species-specific cleavage of the autophagy adaptor p62 dictates responses to TNF.

In Molecular Cell on 16 April 2026 by Nössing, C., Troitskaya, O., et al.

Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

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Preprint on BioRxiv : the Preprint Server for Biology on 2 February 2024 by Shi, H., Wang, X., et al.

CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death.

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In Cell Death and Differentiation on 1 May 2023 by Kuehnle, N., Osborne, S. M., et al.

TRAIL Conjugated Silver Nanoparticle Synthesis, Characterization and Therapeutic Effects on HT-29 Colon Cancer Cells.

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In Iranian Journal of Pharmaceutical Research : IJPR on 28 September 2021 by Birtekocak, F., Demirbolat, G. M., et al.

5-Fluorouracil enhances the chemosensitivity of gastric cancer to TRAIL via inhibition of the MAPK pathway.

View Preprint View PDF

In Biochemical and Biophysical Research Communications on 12 February 2021 by Li, H., Lv, J., et al.

Downregulation of lncRNA ITSN1-2 correlates with decreased disease risk and activity of rheumatoid arthritis (RA), and reduces RA fibroblast-like synoviocytes proliferation and inflammation via inhibiting NOD2/RIP2 signaling pathway.

View PDF

In American Journal of Translational Research on 10 September 2019 by Yue, T., Fan, X., et al.

Designing combination therapies with modeling chaperoned machine learning.

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In PLoS Computational Biology on 1 September 2019 by Zhang, Y., Huynh, J. M., et al.

Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.

View PDF

In Autophagy on 1 September 2016 by Li, X., Zhu, F., et al.

Melanoma antigen-D2: A nucleolar protein undergoing delocalization during cell cycle and after cellular stress.

In Biochimica et Biophysica Acta on 1 April 2016 by Pirlot, C., Thiry, M., et al.

Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy.

View PDF

In Autophagy on 22 January 2015 by Yang, M., Liu, L., et al.

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