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Comments

(2037-C5-025) Recombinant Human Complement Component C5a Protein

Supplied by R&D Systems, cited in 15 publications. Applications used include WB.

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Supplier info
15 citations

General Information

Supplier
R&D Systems
Purified
No
Bioactive
No
Nature
Recombinant
Protein Name
Complement C5
UniProt ID
P01031 - CO5_HUMAN
Species
Homo sapiens (Human)
Gene
C5

Supplier provided information

Applications

None provided

Reactivity

  • Homo sapiens (Human)

Additional product information

Synonyms

C5, C5A, HE

Protein Names

Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CO5_HUMAN

UniProt Code History

P01031, Q14CJ0, Q27I61

Gene

C5, CPAMD4, C5a, C5D, C5b, ECLZB


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0 images
15 citations

found in the literature

Applications
  • WB
Reactivity
  • None Available
Dilutions
  • None Available

Published images

We have not yet identified suitable images that show this product being used, more are being added all the time.

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Complement C5a Promotes Epithelial-Mesenchymal Transition in Pterygium via C5aR Activation.

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In Investigative Ophthalmology & Visual Science on 1 June 2026 by Han, J., Gong, Q., et al.

P-Rex1 controls phagocytosis and the killing of bacteria by murine neutrophils independently of its catalytic activity.

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In Frontiers in Immunology on 16 October 2025 by Islam, P., Chu, J. Y., et al.

C5a-Induced Autophagy Dysfunction Promotes Choroidal Neovascularization Through the ROS-Inflammatory Pathway.

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In Investigative Ophthalmology & Visual Science on 1 July 2025 by Du, Y., Feng, L., et al.

Applications:

WB

The GPCR adaptor protein Norbin controls the trafficking of C5aR1 and CXCR4 in mouse neutrophils.

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In The Journal of Biological Chemistry on 1 December 2024 by Chetwynd, S. A., Ward, R. J., et al.

Mononuclear phagocyte morphological response to chemoattractants is dependent on geranylgeranyl pyrophosphate.

In American Journal of Physiology - Endocrinology and Metabolism on 1 July 2024 by Krauklis, S. A., Hussain, J., et al.

The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B Streptococcus Infection via Cross-Reactive IgG Targeting Virulence Factor C5a Peptidase.

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In Vaccines on 3 December 2023 by McCabe, S., Bjanes, E., et al.

C5a/C5aR1 axis as a key driver promotes epithelial-to-mesenchymal transition in airway epithelial cells in silica nanoparticles-induced pulmonary fibrosis.

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In International Immunopharmacology on 1 December 2023 by Zhou, S., Wang, Z., et al.

A combination of BR101801 and venetoclax enhances antitumor effect in DLBCL cells via c-Myc/Bcl-2/Mcl-1 triple targeting.

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In American Journal of Cancer Research on 11 March 2023 by Jeon, B., Lee, Y. J., et al.

Neutrophil-activating therapy for the treatment of cancer.

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In Cancer Cell on 13 February 2023 by Linde, I. L., Prestwood, T. R., et al.

Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

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In Cell Reports Medicine on 20 April 2021 by Margaroli, C., Moncada-Giraldo, D., et al.

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