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310 results for MDM2 biochemicals

Nutlin-3

3984 is a biochemical from Tocris Bioscience

27 Citations

PubChem CID:

16755649

Common Name:

nutlin-3B

Classification:

Bioactive compound

InChIKey:

BDUHCSBCVGXTJM-IZLXSDGUSA-N

Molecular Weight:

581.5 g/mol

Fig.2.B from the publication: In vitro screening of compounds for targeting gastric cancer with Y220C p53 mutation: a molecule combining zinc chelation and a Michael acceptor drives CDKN1 and BBC3 expression to restore a p53-dependent cytotoxicity.

8 published images

MDM2 Antagonist, Nutlin-3, Racemic

444143 is a biochemical from MM

17 Citations

PubChem CID:

216345

Common Name:

4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one

Classification:

Lipid

InChIKey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Molecular Weight:

581.5 g/mol

Pifithrin-μ

2653 is a biochemical from Tocris Bioscience

14 Citations

PubChem CID:

327653

Common Name:

2-Phenylethynesulfonamide

Classification:

Sulfone

InChIKey:

ZZUZYEMRHCMVTB-UHFFFAOYSA-N

Molecular Weight:

181.21 g/mol

Nutlin 3a

6075 is a biochemical from Tocris Bioscience

10 Citations

PubChem CID:

11433190

Common Name:

Nutlin 3

Classification:

Bioactive compound

InChIKey:

BDUHCSBCVGXTJM-WUFINQPMSA-N

Molecular Weight:

581.5 g/mol

Fig.4.A from the publication: Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity.

1 published image

Nutlin-3

444151 is a biochemical from MM

8 Citations

PubChem CID:

Unknown

Classification:

Bioactive compound

InChIKey:

Unknown

Molecular Weight:

Unknown

Fig.8.B from the publication: USP7 Inhibition Suppresses Neuroblastoma Growth via Induction of p53-Mediated Apoptosis and EZH2 and N-Myc Downregulation.

2 published images

MDM2 Antagonist IV, Nutlin-3a - Calbiochem

444152 is a biochemical from MM

7 Citations

PubChem CID:

Unknown

Classification:

Peptide

InChIKey:

Unknown

Molecular Weight:

Unknown

p53 Activator III, RITA

506149 is a biochemical from MM

7 Citations

PubChem CID:

374536

Common Name:

2,5-Bis(5-hydroxymethyl-2-thienyl)furan

Classification:

Heterocyclic compound

InChIKey:

KZENBFUSKMWCJF-UHFFFAOYSA-N

Molecular Weight:

292.4 g/mol

MDM2 Inhibitor VII, MEL23

373227 is a biochemical from MM

5 Citations

PubChem CID:

Unknown

Classification:

Bioactive compound

InChIKey:

Unknown

Molecular Weight:

Unknown

Fig.3.A from the publication: Analysis of p53-Independent Functions of the Mdm2-MdmX Complex Using Data-Independent Acquisition-Based Profiling.

5 published images

Hdm2 E3 Ligase Inhibitor - Calbiochem

373225 is a biochemical from MM

5 Citations

PubChem CID:

561512

Common Name:

3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide

Classification:

Bioactive compound

InChIKey:

SKFRRPUNXSXVKN-UHFFFAOYSA-N

Molecular Weight:

350.24 g/mol

MDM2/MDMX Dual Inhibitor, RO-5963 - Calbiochem

444153 is a biochemical from MM

4 Citations

PubChem CID:

Unknown

Classification:

Bioactive compound

InChIKey:

Unknown

Molecular Weight:

Unknown

Hdm2 E3 Ligase Inhibitor II, HLI373 - Calbiochem

373226 is a biochemical from MM

4 Citations

PubChem CID:

435678

Common Name:

CID 435678

Classification:

Lipid

InChIKey:

LNRUPMPQQGPSQT-UHFFFAOYSA-N

Molecular Weight:

341.4 g/mol

RITA

2443 is a biochemical from Tocris Bioscience

3 Citations

PubChem CID:

374536

Common Name:

2,5-Bis(5-hydroxymethyl-2-thienyl)furan

Classification:

Heterocyclic compound

InChIKey:

KZENBFUSKMWCJF-UHFFFAOYSA-N

Molecular Weight:

292.4 g/mol

RG7388

A3763 is a biochemical from ApexBio

3 Citations

PubChem CID:

11534420

Common Name:

Retaspimycin

Classification:

Quinone

InChIKey:

OAKGNIRUXAZDQF-TXHRRWQRSA-N

Molecular Weight:

587.7 g/mol

(±)-Nutlin-3, MDM2 antagonist

ab120646 is a biochemical from Abcam

3 Citations

PubChem CID:

216345

Common Name:

4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one

Classification:

Lipid

InChIKey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Molecular Weight:

581.5 g/mol

Nutlin-C1-amido-PEG4-C2-N3

HY-128832 is a biochemical from MedChemExpress

2 Citations

PubChem CID:

138911378

Common Name:

Nutlin-C1-amido-PEG4-C2-N3

InChIKey:

YLHONJUOEKAZKP-PVXQIPPMSA-N

Molecular Weight:

883.8 g/mol

MTBP peptide

ab6235 is a biochemical from Abcam

2 Citations

PubChem CID:

Unknown

Classification:

Peptide

InChIKey:

Unknown

Molecular Weight:

Unknown

Idasanutlin

6904 is a biochemical from Tocris Bioscience

2 Citations

PubChem CID:

53358942

Common Name:

Idasanutlin

Classification:

Carboxylic acid

InChIKey:

TVTXCJFHQKSQQM-LJQIRTBHSA-N

Molecular Weight:

616.5 g/mol

NUTLIN 3A (Mdm2 inhibitor)

SC4368 is a biochemical from Beyotime Biotechnology

2 Citations

PubChem CID:

Unknown

Classification:

Bioactive compound

InChIKey:

Unknown

Molecular Weight:

Unknown

Nutlin-3

A4228 is a biochemical from ApexBio

2 Citations

PubChem CID:

42640

Common Name:

4-(4-Methyl-1-piperazinyl)-7-nitro-2,1,3-benzoxadiazole 3-oxide

Classification:

Heterocyclic compound

InChIKey:

MWFZDJLPWDCQIL-UHFFFAOYSA-N

Molecular Weight:

279.25 g/mol

RITA (NSC 652287)

A4202 is a biochemical from ApexBio

2 Citations

PubChem CID:

72943187

Common Name:

Bromosporine

Classification:

Bioactive compound

InChIKey:

UYBRROMMFMPJAN-UHFFFAOYSA-N

Molecular Weight:

404.4 g/mol

Fig.6.B from the publication: Calcium/P53/Ninjurin 1 Signaling Mediates Plasma Membrane Rupture of Acinar Cells in Severe Acute Pancreatitis.

4 published images

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310 results for MDM2 biochemicals

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Structural Classification

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310 results for MDM2 biochemicals

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