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1,263 results for PI3 biochemicals

Wortmannin

1232 is a biochemical from Tocris Bioscience

203 Citations

PubChem CID:

3003565

Common Name:

Wortmannin from Penicillium funiculosum

Classification:

Bioactive compound

InChIKey:

QDLHCMPXEPAAMD-ZGSWIPFCSA-N

Molecular Weight:

428.4 g/mol

Fig.7.C from the publication: Structural Variants of Dermatan Sulfate Can Affect the Expression of Proteins Involved in Breast Cancer Cell Survival.

19 published images

LY 294002 hydrochloride

1130 is a biochemical from Tocris Bioscience

172 Citations

PubChem CID:

11957589

Common Name:

2-Morpholin-4-yl-8-phenylchromen-4-one;hydrochloride

Classification:

Bioactive compound

InChIKey:

OQZQSRICUOWBLW-UHFFFAOYSA-N

Molecular Weight:

343.8 g/mol

Fig.3.D showing Western Blotting from the publication: PI3K regulates TAZ/YAP and mTORC1 axes that can be synergistically targeted.

9 published images

Rapamycin (Sirolimus)

A8167 is a biochemical from ApexBio

71 Citations

PubChem CID:

5284616

Common Name:

Sirolimus

Classification:

Bioactive compound

InChIKey:

QFJCIRLUMZQUOT-HPLJOQBZSA-N

Molecular Weight:

914.2 g/mol

Fig.3.D from the publication: STAT6/LINC01637 axis regulates tumor growth via autophagy and pharmacological targeting STAT6 as a novel strategy for uveal melanoma.

16 published images

LY 294002, PI3-kinase inhibitor

ab120243 is a biochemical from Abcam

55 Citations

PubChem CID:

3973

Common Name:

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

Classification:

Bioactive compound

InChIKey:

CZQHHVNHHHRRDU-UHFFFAOYSA-N

Molecular Weight:

307.3 g/mol

Fig.4.C from the publication: Targeting the leptin receptor promotes MDA-MB-231 cells' metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.

15 published images

740 Y-P

1983 is a biochemical from Tocris Bioscience

27 Citations

PubChem CID:

90488730

Common Name:

Pdgfr 740Y-P

Classification:

Peptide

InChIKey:

XCGMILZGRGEWHL-QYGSNONCSA-N

Molecular Weight:

3270.7 g/mol

Fig.5.F showing Western Blotting from the publication: Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis.

7 published images

LY 294002

A8250 is a biochemical from ApexBio

26 Citations

PubChem CID:

123964

Common Name:

5,6-Dimethylxanthenone-4-Acetic Acid

Classification:

Heterocyclic compound

InChIKey:

XGOYIMQSIKSOBS-UHFFFAOYSA-N

Molecular Weight:

282.29 g/mol

Fig.4.G from the publication: Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis.

6 published images

CHIR-99021 (CT99021)

A3011 is a biochemical from ApexBio

25 Citations

PubChem CID:

24978538

Common Name:

Abt 263

Classification:

Bioactive compound

InChIKey:

JLYAXFNOILIKPP-KXQOOQHDSA-N

Molecular Weight:

974.6 g/mol

Fig.3.C from the publication: Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.

1 published image

Torin 1

A8312 is a biochemical from ApexBio

21 Citations

PubChem CID:

49836027

Common Name:

1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one

Classification:

Bioactive compound

InChIKey:

AKCRNFFTGXBONI-UHFFFAOYSA-N

Molecular Weight:

607.6 g/mol

Fig.4.D from the publication: mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.

6 published images

Wortmannin, PI3-kinase inhibitor

ab120148 is a biochemical from Abcam

19 Citations

PubChem CID:

312145

Common Name:

Wortmannin

Classification:

Bioactive compound

InChIKey:

QDLHCMPXEPAAMD-QAIWCSMKSA-N

Molecular Weight:

428.4 g/mol

3-Methyladenine

3977 is a biochemical from Tocris Bioscience

18 Citations

PubChem CID:

1673

Common Name:

CID 1673

Classification:

Bioactive compound

InChIKey:

FSASIHFSFGAIJM-UHFFFAOYSA-N

Molecular Weight:

149.15 g/mol

MK-2206 dihydrochloride

A3010 is a biochemical from ApexBio

17 Citations

PubChem CID:

24788740

Common Name:

Ipatasertib

Classification:

Heterocyclic compound

InChIKey:

GRZXWCHAXNAUHY-NSISKUIASA-N

Molecular Weight:

458.0 g/mol

Fig.6.B from the publication: Single-base editing in IGF2 improves meat production and intramuscular fat deposition in Liang Guang Small Spotted pigs.

4 published images

PI3K/AKT-IN-1

HY-144806 is a biochemical from MedChemExpress

15 Citations

PubChem CID:

163322289

Common Name:

4-(4-Methoxyphenyl)-2-(methylthio)-6-(2-(3,4,5-trimethoxybenzyl)hydrazineyl)pyrimidine-5-carbonitrile

InChIKey:

AEWMRSCSIPYZAJ-UHFFFAOYSA-N

Molecular Weight:

467.5 g/mol

Fig.5.D showing Western Blotting from the publication: Pregnane X receptor protects against age-related bone loss in males via PI3K/Akt-mediated inhibition of apoptosis.

11 published images

Quercetin

1125 is a biochemical from Tocris Bioscience

13 Citations

PubChem CID:

5280343

Common Name:

Quercetin

Classification:

Lipid

InChIKey:

REFJWTPEDVJJIY-UHFFFAOYSA-N

Molecular Weight:

302.23 g/mol

Fig.6.D from the publication: Therapeutic potential of flavonols in the treatment of JCPyV.

8 published images

PI3K-IN-1

HY-12068 is a biochemical from MedChemExpress

11 Citations

PubChem CID:

49867926

Common Name:

N-(4-(N-(3-((3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide

Classification:

Sulfone

InChIKey:

HJSSPYJVWLTYHG-UHFFFAOYSA-N

Molecular Weight:

599.7 g/mol

Fig.3.E showing Western Blotting from the publication: Astrocyte-derived Interleukin-31 causes poor prognosis in elderly patients with intracerebral hemorrhage.

7 published images

PI 828

2814 is a biochemical from Tocris Bioscience

9 Citations

PubChem CID:

25181195

Common Name:

8-(4-Aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one

InChIKey:

WUKMIBOGGXMBAC-UHFFFAOYSA-N

Molecular Weight:

322.4 g/mol

Fig.8.A from the publication: In vitro differentiated human CD4+ T cells produce hepatocyte growth factor.

2 published images

PI-103 (PI3-K alpha Inhibitor 1)

B-0303 is a biochemical from Echelon

9 Citations

PubChem CID:

9884685

Common Name:

3-(4-(4-Morpholinyl)pyrido(3',2':4,5)furo(3,2-d)pyrimidin-2-yl)phenol

Classification:

Bioactive compound

InChIKey:

TUVCWJQQGGETHL-UHFFFAOYSA-N

Molecular Weight:

348.4 g/mol

Everolimus (RAD001)

A8169 is a biochemical from ApexBio

8 Citations

PubChem CID:

Unknown

InChIKey:

Unknown

Molecular Weight:

958.22 g/mol

Fig.6.G from the publication: Systematic analysis of prognostic and immunologic characteristics associated with coronavirus disease 2019 regulators in acute myeloid leukemia.

1 published image

Urolithin A

6762 is a biochemical from Tocris Bioscience

7 Citations

PubChem CID:

5488186

Common Name:

Urolithin A

Classification:

Heterocyclic compound

InChIKey:

RIUPLDUFZCXCHM-UHFFFAOYSA-N

Molecular Weight:

228.2 g/mol

Fig.2.C showing Flow cytometry/Cell sorting from the publication: Urolithin A increases the natural killer activity of PBMCs in patients with prostate cancer.

6 published images

LY294002 (PI3-K Inhibitor)

B-0294 is a biochemical from Echelon

7 Citations

PubChem CID:

3973

Common Name:

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

Classification:

Bioactive compound

InChIKey:

CZQHHVNHHHRRDU-UHFFFAOYSA-N

Molecular Weight:

307.3 g/mol

iMDK

5126 is a biochemical from Tocris Bioscience

6 Citations

PubChem CID:

15991416

Common Name:

3-[2-(4-fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl]-2H-chromen-2-one

InChIKey:

IWFKQTWYILKFGE-UHFFFAOYSA-N

Molecular Weight:

376.4 g/mol

Fig.6.G from the publication: BAG2, MAD2L1, and MDK are cancer-driver genes and candidate targets for novel therapies in malignant pleural mesothelioma.

6 published images

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1,263 results for PI3 biochemicals

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1,263 results for PI3 biochemicals

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