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Reagent type

  • Antibodies (720)
  • Biochemicals (42)
  • Experimental Models (14)
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  • Proteins (39)

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Structural Classification
  • Bioactive compound (16)
  • Heterocyclic compound (5)
  • Lipid (2)
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  • Amine (2)
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  • Sulfone (1)
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Function
  • Inhibitor (20)
  • Activator (4)
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  • Tocris Bioscience (41)
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42 results for ESCS biochemicals

Dorsomorphin dihydrochloride
3093 is a biochemical from Tocris Bioscience
283 Citations
PubChem CID:
49761481
Common Name:
Dorsomorphin dihydrochloride
Classification:
Bioactive compound
InChIKey:
RJDVIJJQKMGPMV-UHFFFAOYSA-N
Molecular Weight:
472.4 g/mol
Fig.3.A showing Western Blotting from the publication: Oxidized MIF is an Alzheimer's disease drug target relaying external risk factors to tau pathology.

7 published images

Rapamycin
1292 is a biochemical from Tocris Bioscience
224 Citations
PubChem CID:
5284616
Common Name:
Sirolimus
Classification:
Bioactive compound
InChIKey:
QFJCIRLUMZQUOT-HPLJOQBZSA-N
Molecular Weight:
914.2 g/mol
Fig.3.K showing Western Blotting from the publication: Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry.

57 published images

DMH-1
4126 is a biochemical from Tocris Bioscience
143 Citations
PubChem CID:
50997747
Common Name:
4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Classification:
Heterocyclic compound
InChIKey:
JMIFGARJSWXZSH-UHFFFAOYSA-N
Molecular Weight:
380.4 g/mol
Fig.6.A from the publication: BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling.

8 published images

Wnt-C59
5148 is a biochemical from Tocris Bioscience
138 Citations
PubChem CID:
57519544
Common Name:
2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide
Classification:
Bioactive compound
InChIKey:
KHZOJCQBHJUJFY-UHFFFAOYSA-N
Molecular Weight:
379.5 g/mol
Fig.7.A from the publication: Primary cilia promote the differentiation of human neurons through the WNT signaling pathway.

20 published images

LDN 193189 dihydrochloride
6053 is a biochemical from Tocris Bioscience
135 Citations
PubChem CID:
91900717
Common Name:
LDN 193189 dihydrochloride
Classification:
Bioactive compound
InChIKey:
CMQXLLAILGGLRV-UHFFFAOYSA-N
Molecular Weight:
479.4 g/mol
Fig.2.H from the publication: Inhibition of Wnt signaling in primary human hepatocytes promotes Plasmodium falciparum liver stage development.

4 published images

DMSO, sterile filtered
3176 is a biochemical from Tocris Bioscience
64 Citations
PubChem CID:
679
Common Name:
Dimethyl Sulfoxide
Classification:
Sulfoxide
InChIKey:
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
Molecular Weight:
78.14 g/mol
Fig.5.C from the publication: Synergistic Efficacy of Gedatolisib and Darolutamide in Prostate Cancer to Overcome Resistance to Androgen-Targeted Therapy.

12 published images

Thiazovivin
3845 is a biochemical from Tocris Bioscience
58 Citations
PubChem CID:
46209426
Common Name:
Thiazovivin
Classification:
Bioactive compound
InChIKey:
DOBKQCZBPPCLEG-UHFFFAOYSA-N
Molecular Weight:
311.4 g/mol
Cyclopamine
1623 is a biochemical from Tocris Bioscience
54 Citations
PubChem CID:
442972
Common Name:
Cyclopamine
Classification:
Bioactive compound
InChIKey:
QASFUMOKHFSJGL-LAFRSMQTSA-N
Molecular Weight:
411.6 g/mol
Fig.7.G from the publication: Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells.

10 published images

Retinoic acid
0695 is a biochemical from Tocris Bioscience
53 Citations
PubChem CID:
444795
Common Name:
Retinoic Acid
Classification:
Lipid
InChIKey:
SHGAZHPCJJPHSC-YCNIQYBTSA-N
Molecular Weight:
300.4 g/mol
Fig.3.B from the publication: Mesenchymal WNT signaling coordinates epithelial and mesenchymal differentiation in the developing murine ureter.

2 published images

1-EBIO
1041 is a biochemical from Tocris Bioscience
48 Citations
PubChem CID:
82320
Common Name:
1-Ebio
Classification:
Heterocyclic compound
InChIKey:
CXUCKELNYMZTRT-UHFFFAOYSA-N
Molecular Weight:
162.19 g/mol
Dibutyryl-cAMP, sodium salt
1141 is a biochemical from Tocris Bioscience
40 Citations
PubChem CID:
23663967
Common Name:
Bucladesine Sodium
Classification:
Nucleotide
InChIKey:
KRBZRVBLIUDQNG-JBVYASIDSA-M
Molecular Weight:
491.4 g/mol
SAG
4366 is a biochemical from Tocris Bioscience
40 Citations
PubChem CID:
5284330
Common Name:
Sag1.3
Classification:
Bioactive compound
InChIKey:
VFSUUTYAEQOIMW-UHFFFAOYSA-N
Molecular Weight:
490.1 g/mol
Fig.1.D showing Immunohistochemistry-immunofluorescence from the publication: A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.

32 published images

IWP 4
5214 is a biochemical from Tocris Bioscience
37 Citations
PubChem CID:
2155264
Common Name:
2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
Classification:
Bioactive compound
InChIKey:
RHUJMHOIQBDFQR-UHFFFAOYSA-N
Molecular Weight:
496.6 g/mol
Fig.1.B from the publication: Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling.

5 published images

Centrinone
5687 is a biochemical from Tocris Bioscience
25 Citations
PubChem CID:
91801159
Common Name:
Centrinone
Classification:
Sulfone
InChIKey:
HHJSKDRCUMVWKF-UHFFFAOYSA-N
Molecular Weight:
633.7 g/mol
Fig.1.B showing Immunocytochemistry-immunofluorescence from the publication: A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation.

15 published images

EC 23
4011 is a biochemical from Tocris Bioscience
20 Citations
PubChem CID:
10314719
Common Name:
Agn-190205
Classification:
Carboxylic acid
InChIKey:
OQVLOWLEEHYBJH-UHFFFAOYSA-N
Molecular Weight:
332.4 g/mol
CCG 1423
5233 is a biochemical from Tocris Bioscience
10 Citations
PubChem CID:
2726015
Common Name:
Ccg-1423
Classification:
Amine
InChIKey:
DSMXVSGJIDFLKP-UHFFFAOYSA-N
Molecular Weight:
454.7 g/mol
Fig.5.A from the publication: Pyrin inflammasome-driven erosive arthritis caused by unprenylated RHO GTPase signaling.

5 published images

Pyridone 6
6577 is a biochemical from Tocris Bioscience
10 Citations
PubChem CID:
5494425
Common Name:
Pyridone 6
Classification:
Bioactive compound
InChIKey:
VNDWQCSOSCCWIP-UHFFFAOYSA-N
Molecular Weight:
309.3 g/mol
Fig.2.E from the publication: ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs.

3 published images

I-BET 151 dihydrochloride
4650 is a biochemical from Tocris Bioscience
10 Citations
PubChem CID:
170320
Common Name:
Elacridar Hydrochloride
Classification:
Bioactive compound
InChIKey:
IQOJZZHRYSSFJM-UHFFFAOYSA-N
Molecular Weight:
600.1 g/mol
Fig.3.E from the publication: Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer.

2 published images

STF 31
4484 is a biochemical from Tocris Bioscience
9 Citations
PubChem CID:
984333
Common Name:
Stf-31
Classification:
Heterocyclic compound
InChIKey:
NGQPRVWTFNBUHA-UHFFFAOYSA-N
Molecular Weight:
423.5 g/mol
IDE 1
4015 is a biochemical from Tocris Bioscience
7 Citations
PubChem CID:
66974738
Common Name:
2-[(6-Carboxyhexanoylhydrazinylidene)methyl]benzoic acid
InChIKey:
ABKJCDILEUEJSH-UHFFFAOYSA-N
Molecular Weight:
306.31 g/mol
Fig.4.B from the publication: A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit.

1 published image

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